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Apoptosis > Apoptosis Kits > M30 Apoptosense
Catalog Number:P10011 (formerly P10010)
Packaging:1 kit, 96 deteminations

Please Note New Catalog Number: P10011

Research Use Only

M30 Apoptosense® ELISA is a unique tool for reliable and reproducible quantitative detection of apoptosis of keratin 18 (K18) (cytokeratin 18 [CK18]) positive cells. The assay is intended for subject sera. Another useful application is the detection of tumor apoptosis in mouse xenograft models using plasma samples.

M30 Apoptosense® is an ELISA assay based on the M30 monoclonal antibody
(Leers et al., 1999).
This antibody specifically binds caspase-cleaved keratin 18 (ccK18, caspase-celaved cytokeratin 18, ccCK18 or K18-Asp396) but does not bind native, uncleaved, K18. The M30 Apoptosense® assay therefore represents a specific quantitative test for apoptosis in epithelial cells (Hägg et al. 2002).

All reagents are provided in a convenient ready-for-use format. The separable strips provide the flexibility for your experimental design. 



Download File Type File Size
M30 Apoptosense ELISA Data Sheet PDF File 128.17 KB
M30 Apoptosense ELISA Instructions for Use PDF File 272.72 KB
Accumulation of K18 Products Over Time (presentation) PDF File 171.01 KB

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