DiaPharma Group, Inc.

For the determination of Heparin in plasma. Antithrombin in conjunction with heparine like substances is a potent inhibitor of thrombin, factor Xa, factor Xla and factor lXa.

Antithrombin is prepared from human plasma and purified by affinity chromatography with an Heparine Sepharose gel according to the protocol of Miller-Andersson et al. (Thromb. Res. 5, 439-452, 1974).

Reagent -- Composition, Packaging, Storage and Stability

• Lyophilized human Antithrombin 10 lU ± 1
• Albumin 12 mg
• Sodium Chloride 9 mg

The lyophilized powder is stable at 2-8°C until the expiry date printed on the label. The reconstituted Antithrombin is stable for 1 month at 2-8°C or 6 months at -20°C when used for the determination of Heparin, according to the test conditions of Coatest® Heparin.

Specific Activity

Above 6 IU/mg Antithrombin.

Composition and purity
Lyophilized powder prepared from human plasma after affinity chromatography on heparin-Sepharose gel. Contains human albumin as a stabilizer.

Note: This preparation is not a standard.

Antithrombin and Related Products Available:

• Human Antithrombin (Cat. No. B820720) (820720) 10 IU
• Human Antithrombin (Cat. No. B810796) (810796) 25 IU
• Human Antithrombin (Cat. No. DPGHAT-50) 50 IU
• Human Antithrombin (Cat. No. B821497) (821497) 500 IU
• Human Antithrombin (Cat. No. PP004A) 150 µg (1 mL-1 PEU)
• Human Antithrombin (Cat. No. PP004K) 6 x 150 µg
• Human Antithrombin (Cat. No. PP004B) 1.5 mg (1 mL-10 PEU)
• Human Antithrombin (Cat. No. PP004D) 3.75 mg (1 mL-25 PEU)
• Human Antithrombin (Cat. No. PP004C) 10 mg (2 mL-Grade 1)
• Bovine Antithrombin (Cat. No. BP104C) (BP104C) 10 mg (2 ml)
• Coatest Heparin (Cat. No. K255539) (K255539) 1 kit
• Liquid Antithrombin Substrate (Cat. No. 0020002600) 6 x 2 ml