Antiphospholipid

Define anti-phospholipid antibodies and anti-phospholipid antibody cofactor.

Antiphospholipid antibodies are a heterogeneous group of auto-antibodies (IgG, IgM, and IgA)...

Describe a laboratory algorithm for testing for anticardiolipin antibodies.
Describe the anti-phospholipid Syndrome (APS), including the laboratory criteria for diagnosis.

APS is a disorder which is often associated with certain autoimmune disorders, such as lupus...

Describe the location and function of the various phospholipids including: cardiolipin (CL), phosphatidylserine (PS), phosphatidylethanolamine (PE), phosphatidylcholine (PC), and phosphatidylinsitol (PI).
  • Cardiolipin (diphosphatidylglycerol) (CL) - located in the inner mitochondrial...
How does a syphilis infection affect the REAADS anti-cardiolipin test?

Patients with current or prior syphilis infections may have a positive result without increa...

Is administering one test sufficient for diagnosis?

No, it has been decided that more than one test is should be performed. For example, a coagu...

List some phospholipid cofactors.