Coamatic Factor VIII

Hemophilia A mutations associated with 1-stage/2-stage activity discrepancy disrupt protein-protein interactions within the triplicated A domains of thrombin-activated factor VIIIa.
Pipe SW, Saenko EL, Eickhorst AN, Kemball-Cook G, Kaufman RJ.
Blood. 2001 Feb 1;97(3):685-91.
PMID: 11157485

Stability and sterility of a recombinant factor VIII concentrate prepared for continuous infusion administration.
Belgaumi AF, Patrick CC, Deitcher SR.
Am J Hematol. 1999 Sep;62(1):13-8.
PMID: 10467271

Mild hemophilia A caused by increased rate of factor VIII A2 subunit dissociation: evidence for nonproteolytic inactivation of factor VIIIa in vivo.
Pipe SW, Eickhorst AN, McKinley SH, Saenko EL, Kaufman RJ.
Blood. 1999 Jan 1;93(1):176-83.
PMID: 9864159

Chandler WL et al. Comparison of Three Methods for Measuring Factor VIII Levels in Plasma.
American Journal of Clinical Pathology
2003;120:34-39.

PMID (PubMed - indexed for MEDLINE)