Each antibody listed has been tested for reactivity to the plasma of a variety of species. The double immunodiffusion (DID) technique used tests the ability of an antibody to precipitate an antigen in an agarose gel. The DID technique has limitations and a negative result should not necessarily be interpreted as non-recognition of an antigen. A number of antibodies may react with fewer recognition sites on the antigen of another species and be unable to form an insoluble immune complex (this is observed with many monoclonal antibodies). An antibody may demonstrate a greater spectrum of cross reactivity in applications such as immunoblotting and immunohistochemistry where antigen precipitation is not required. Below are examples of typical results seen in historical lots. See product insert for lot specific testing results.
|
Antibodies to: |
Prod # |
Human |
Rat |
Mouse |
Rabbit |
|
human Fibrinogen |
SAFG-IG |
*** |
** |
-- |
** |
|
human Fibrinogen fragment E |
SAFNE-IG |
*** |
-- |
-- |
-- |
|
rabbit Fibrinogen |
SARFG-IG |
*** |
*** |
*** |
*** |
|
rat Fibrinogen |
SARTF-IG |
*** |
*** |
*** |
*** |
|
canine Fibrinogen |
SACFG-IG |
*** |
*** |
*** |
*** |
|
human Prothrombin |
SAFII-IG |
*** |
-- |
-- |
-- |
|
human Thrombin |
SAHT-IG |
*** |
* |
-- |
-- |
|
rabbit Thrombin |
SART-IG |
-- |
-- |
-- |
*** |
|
bovine Thrombin |
SABT-IG |
-- |
-- |
-- |
-- |
|
human Factor V |
SAFV-IG |
*** |
-- |
-- |
* |
|
bovine Factor V |
SABFV-IG |
-- |
-- |
-- |
-- |
|
human von Willebrand Factor |
GAVWF-IG |
*** |
** |
-- |
** |
|
human Factor IX (F.IX) |
GAFIX-IG |
*** |
-- |
-- |
** |
|
human Factor X (F.X) |
GAFX-IG |
*** |
-- |
-- |
-- |
|
human Factor XI (F.XI) |
GAFXI-IG |
*** |
-- |
-- |
-- |
|
human Factor XII (F.XII) |
GAFXII-IG |
*** |
-- |
-- |
-- |
|
human Factor XIII (FXIII) |
SAFXIII-IG |
*** |
-- |
-- |
-- |
|
human Factor XIII-A (A subunit) |
SAF13A-IG |
*** |
** |
* |
** |
|
human Prekallikrein |
SAPK-IG |
*** |
** |
NT |
** |
|
human Protein C (PC) |
SAPC-IG |
*** |
-- |
-- |
-- |
|
GAPC-IG |
*** |
-- |
-- |
-- |
|
|
human Protein S (PS) |
SAPS-IG |
*** |
-- |
-- |
-- |
|
GAPS-IG |
*** |
-- |
-- |
-- |
|
|
human Plasminogen (Pg) |
GAPG-IG |
*** |
** |
-- |
** |
|
human Antithrombin (ATIII) |
SAAT-IG |
*** |
-- |
-- |
-- |
|
GAAT-IG |
*** |
** |
-- |
-- |
|
|
human Heparin Cofactor-II |
GAHC2-IG |
*** |
** |
* |
** |
|
human Protein C Inhibitor (PAI-3) |
GAPCI-IG |
*** |
-- |
-- |
-- |
|
Human a2Antiplasmin (a2AP) |
GA2AP-IG |
*** |
-- |
-- |
-- |
|
human TAFI (carboxypeptidase B) |
SATAFI-IG |
*** |
-- |
-- |
-- |
|
human a1Antitrypsin (a1AT) |
SA1AT-IG |
*** |
-- |
-- |
-- |
|
GA1AT-IG |
*** |
-- |
-- |
-- |
|
|
human a2Macroglobulin |
GA2M-IG |
*** |
-- |
-- |
** |
|
human ß2Glycoprotein-I (Apo-H) |
RAB2GP-IG |
*** |
-- |
-- |
-- |
|
GAB2GP-IG |
*** |
-- |
-- |
-- |
|
|
rabbit ß2Glycoprotein-I (Apo-H) |
SARBG-IG |
* |
* |
* |
*** |
|
human Vitronectin (S-Protein) |
SAVN-IG |
*** |
-- |
-- |
-- |
|
human Complement C1s |
GAC1S-IG |
*** |
-- |
-- |
-- |
|
human C1-Inhibitor (C1-Inh) |
GACINH-IG |
*** |
-- |
-- |
-- |
Legend: *** = strong positive * = weak positive -- = negative NT = not tested
|
Antibodies to: |
Prod # |
Canine |
Feline |
Porcine |
Bovine |
|
human Fibrinogen |
SAFG-IG |
*** |
*** |
* |
-- |
|
human Fibrinogen fragment E |
SAFNE-IG |
-- |
-- |
NT |
-- |
|
rabbit Fibrinogen |
SARFG-IG |
*** |
*** |
NT |
-- |
|
rat Fibrinogen |
SARTF-IG |
*** |
*** |
NT |
-- |
|
canine Fibrinogen |
SACFG-IG |
*** |
*** |
NT |
-- |
|
human Prothrombin |
SAFII-IG |
* |
NT |
-- |
-- |
|
human Thrombin |
SAHT-IG |
-- |
-- |
-- |
-- |
|
rabbit Thrombin |
SART-IG |
-- |
-- |
-- |
-- |
|
bovine Thrombin |
SABT-IG |
-- |
-- |
-- |
*** |
|
human Factor V |
SAFV-IG |
-- |
-- |
-- |
-- |
|
bovine Factor V |
SABFV-IG |
-- |
-- |
-- |
*** |
|
human von Willebrand Factor |
GAVWF-IG |
** |
** |
** |
-- |
|
human Factor IX (F.IX) |
GAFIX-IG |
-- |
-- |
-- |
-- |
|
human Factor X (F.X) |
GAFX-IG |
* |
* |
-- |
-- |
|
human Factor XI (F.XI) |
GAFXI-IG |
-- |
-- |
-- |
-- |
|
human Factor XII (F.XII) |
GAFXII-IG |
-- |
-- |
-- |
-- |
|
human Factor XIII (FXIII) |
SAFXIII-IG |
* |
* |
-- |
-- |
|
human Factor XIII-A (A subunit) |
SAF13A-IG |
-- |
-- |
-- |
-- |
|
human Prekallikrein |
SAPK-IG |
-- |
-- |
-- |
-- |
|
human Protein C (PC) |
SAPC-IG |
-- |
-- |
-- |
-- |
|
GAPC-IG |
-- |
-- |
-- |
-- |
|
|
human Protein S (PS) |
SAPS-IG |
-- |
-- |
-- |
-- |
|
GAPS-IG |
* |
* |
-- |
-- |
|
|
human Plasminogen (Pg) |
GAPG-IG |
** |
** |
** |
* |
|
human Antithrombin (ATIII) |
SAAT-IG |
-- |
-- |
-- |
-- |
|
GAAT-IG |
** |
** |
* |
-- |
|
|
human Heparin Cofactor-II |
GAHC2-IG |
** |
** |
** |
-- |
|
human Protein C Inhibitor (PAI-3) |
GAPCI-IG |
-- |
-- |
** |
-- |
|
Human a2Antiplasmin (a2AP) |
GA2AP-IG |
-- |
-- |
-- |
-- |
|
human TAFI (carboxypeptidase B) |
SATAFI-IG |
-- |
-- |
-- |
-- |
|
human a1Antitrypsin (a1AT) |
SA1AT-IG |
-- |
-- |
-- |
* |
|
GA1AT-IG |
** |
-- |
* |
-- |
|
|
human a2Macroglobulin |
GA2M-IG |
** |
*** |
*** |
*** |
|
human ß2Glycoprotein-I (Apo-H) |
RAB2GP-IG |
-- |
* |
* |
-- |
|
GAB2GP-IG |
-- |
-- |
-- |
-- |
|
|
rabbit ß2Glycoprotein-I (Apo-H) |
SARBG-IG |
* |
* |
-- |
-- |
|
human Vitronectin (S-Protein) |
SAVN-IG |
-- |
-- |
-- |
-- |
|
human Complement C1s |
GAC1S-IG |
-- |
-- |
-- |
-- |
|
human C1-Inhibitor (C1-Inh) |
GACINH-IG |
-- |
-- |
-- |
-- |
Legend: *** = strong positive * = weak positive -- = negative NT = not tested