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alpha2 antiplasmin |
Major inhibitor of plasmin produced and secreted by hepatocytes and stored in platelet alpha granules. |
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Anti-cardiolipin antibodies |
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Non-hereditary diseases or associated conditions that cause the platelets to not function properly. MEDLINEplus |
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Time in seconds required for clot formation in recalcified blood plasma after the addition of contact activators and platelet substitutes (phospholipids). APTT is used to monitor therapy with heparin and other anticoagulants.see also PTT |
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An acquired or inherited condition associated with an increased risk of venous thrombosis and most commonly associated with a mutation in the factor V gene. Patients with APC resistance have limited anticoagulant response to APC. |
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Two prothrombin complex concentrates are purposely "activated" so that they contain some FIX, FX, etc. in active form (FIXa, FXa, etc.). |
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The absence of fibrinogen in the blood. |
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A quantitative assessment of platelet cohesion in a photometer by the detection of changes in light transmission through a suspension of platelets in plasma. The light transmission pattern is analyzed in response to a variety of agonists. |
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Alkaline Phosphatase |
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A platelet storage organelle that contains hemostatic proteins. |
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An organic compound containing an amino group (NH2), a carboxylic acid group (COOH), and any of various side groups, especially any of the 20 compounds that have the basic formula NH2CHRCOOH, and that link together by peptide bonds to form proteins or that function as chemical messengers and as intermediates in metabolism. |
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The study of blood and lymph vessels. Gray's Anatomy |
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A protein produced by the immune system in response to the presence of an antigen. It defends the body against substances identified by the immune system as potentially harmful. MEDLINEplus |
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A substance that prevents the clotting of blood also used in the prophylaxis and treatment of clotting disorders. see also oral anticoagulants |
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Inhibiting the breakdown of fibrin. |
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Plasma IgG, IgM, or IgA antibodies against protein phospholipid complexes. |
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Naturally occurring anticoagulant that inactivates thrombin, factors Xa, IXa, XIa, XIIa, and kallikrein, also enhanced by heparin. Also called Antithrombin III, ATIII. MEDLINEplus |
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A substance that induces the formation of antibodies because it is recognized by the immune system as a threat. It may be a foreign (nonnative) substance from the environment (such as chemicals) or formed within the body (such as bacterial or viral toxins). MEDLINEplus |
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A disorder that is characterized by hypercoagulability due to the presence of antibodies against phospholipids. |
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The main trunk of the systemic arteries, carrying blood from the left side of the heart to the arteries of all limbs and organs except the lungs. Gray's Anatomy |
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Any of various proteins that combine with a lipid to form a lipoprotein and are a constituent of chylomicrons, HDL, LDL, and VLDL. |
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Disintegration of cells into membrane-bound particles that are then eliminated by phagocytosis or by shedding. |
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One of the small terminal branches of an artery, especially one that connects with a capillary. |
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A chronic disease in which thickening, hardening, and loss of elasticity of the arterial walls result in impaired blood circulation. It develops with aging, and in hypertension, diabetes, hyperlipidemia, and other conditions. |
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A form of arteriosclerosis characterized by the deposition of atheromatous plaques containing cholesterol and lipids on the innermost layer of the walls of large and medium-sized arteries. |
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Any of the muscular elastic tubes that form a branching system and that carry blood away from the heart to the cells, tissues, and organs of the body. Gray's Anatomy |